Senior Software Engineer Jobs in San Francisco 2026: Mixedbread is looking for a talented Senior Software Engineer to join its core engineering team and help build the infrastructure behind fast, scalable AI search. This is an exciting opportunity for an experienced engineer who enjoys solving complex technical problems and wants to contribute to technology that is shaping how developers use artificial intelligence.
The successful candidate will work on backend systems, distributed computing, vector databases, model-serving infrastructure, and machine learning services that support millions of requests. You will collaborate closely with experienced engineers and machine learning specialists while helping transform innovative AI technologies into reliable products. The average salary for a Senior Software Engineer in San Francisco is approximately $200,000 per year in 2026, with actual compensation potentially varying based on experience, skills, equity, and other benefits.
This remote full-time position is particularly suitable for someone who enjoys building high-performance systems, improving software reliability, and taking ownership of technically challenging projects. Mixedbread also offers competitive compensation, equity, professional development support, and visa sponsorship and relocation assistance for eligible candidates.
Details of Senior Software Engineer Job:
- Job Title: Senior Software Engineer Jobs in San Francisco 2026
- Hiring Organization: Mixedbread
- Location: San Francisco, California, USA
- Work Arrangement: Remote
- Employment Type: Full-time
- Industry: Artificial Intelligence, Software Development, Machine Learning Infrastructure
About Mixedbread:
Mixedbread creates technologies with an emphasis on machine learning infrastructure, embeddings, and AI search. Large-scale search workloads in over 100 languages are supported by its systems, and its models are made to function in a variety of settings, from powerful GPU infrastructure to mobile devices.
Becoming a member of the engineering team entails working at the nexus of distributed systems, software engineering, artificial intelligence, and search technologies. Instead of just creating another traditional software product, this position offers engineers the chance to contribute to crucial infrastructure if they want their work to have a significant impact on the future of AI applications.
Responsibilities for Senior Software Engineer Jobs in San Francisco:
As a Senior Software Engineer, you will contribute to the design, development, and continuous improvement of Mixedbread’s core engineering infrastructure.
- Design and develop scalable backend services capable of processing millions of embedding and search requests.
- Optimize vector database technology to achieve extremely fast query performance at large scale.
- Build, improve, and maintain model-serving infrastructure across different deployment environments.
- Work closely with machine learning engineers to bring new models and algorithms into production.
- Improve monitoring, observability, availability, and reliability across distributed systems.
- Participate in important technical architecture and engineering decisions.
- Mentor junior engineers and help promote strong engineering practices across the team.
- Write clean, maintainable, well-tested production code.
- Identify performance bottlenecks and develop practical solutions for large-scale workloads.
- Contribute to the continued improvement of engineering processes, infrastructure, and development standards.
Required Qualifications:
Mixedbread is seeking an engineer with strong software development experience and a genuine interest in high-performance systems and AI infrastructure.
- Professional production experience with Python, Go, Rust, or similar programming languages.
- Strong understanding of distributed systems and database internals.
- Experience working with vector databases, search engines, or machine learning infrastructure.
- Demonstrated experience designing, building, and scaling high-performance software systems.
- Strong problem-solving and analytical abilities.
- Excellent written and verbal communication skills.
- Ability to work effectively in a remote-first engineering environment.
- Bachelor’s degree in Computer Science or a related discipline, or equivalent practical experience.
Preferred Qualifications:
Candidates may be particularly qualified for this role if they have further experience in the following fields:
- familiarity with model optimization technologies such as TensorRT or ONNX.
- contributions to open-source infrastructure or machine learning initiatives.
- knowledge of embedding models and transformer designs.
- familiarity with Ray, Kubernetes, or similar orchestration tools.
- understanding of AI search systems, natural language processing, or information retrieval.
- expertise in system optimization for low latency and high throughput.
- prior experience developing AI infrastructure or APIs for developers.
Salary and Compensation:
For a Senior Software Engineer in San Francisco, the average base salary in 2026 is approximately $200,000 per year, although compensation varies by experience, technical skills, employer, equity, and bonuses. Current salary data places the average around $198,000–$201,000, while total compensation can be considerably higher when equity and bonuses are included.
Benefits of Senior Software Engineer Job:
- Competitive Pay and Equity: Workers can take part in the long-term expansion and success of the business by receiving competitive pay and equity chances.
- Health, Dental, and Vision Coverage: While pursuing their personal and professional objectives, employees and their families can obtain essential medical, dental, and vision treatments thanks to comprehensive healthcare benefits.
- Visa Sponsorship and Relocation Support: Qualified engineers have the chance to pursue an interesting career in the United States by applying for visa sponsorship and relocation aid.
- Professional Development Support: A budget for professional development enables staff members to stay up to date on fast-developing AI technology, attend pertinent events, enhance their technical skills, and continue learning.
- AI Tools and Subscriptions: Workers have access to top-notch AI tools and subscriptions that can help with daily engineering tasks, experimentation, productivity, and research.
- Wellness and Lifestyle Benefits: Gym memberships and sports club subscriptions are examples of wellness support that can help staff workers strike a healthy balance between their personal well-being and rigorous technical work.
Check Also: Azure Cloud Engineer Jobs in USA with Visa Sponsorship
Why Consider This Opportunity?
A career in AI infrastructure can be especially rewarding for engineers who want to work on problems that extend beyond traditional application development. At Mixedbread, your work can influence the systems developers rely on when building modern AI-powered products.
The role offers the chance to work with distributed systems, search technology, databases, model serving, and machine learning in one position. You will not simply be maintaining existing software; you will help improve the underlying infrastructure that makes AI search faster, more reliable, and more accessible.
For an experienced engineer who enjoys learning, solving difficult problems, and collaborating with talented technical teams, this could be a meaningful next step in a growing AI-focused career.
Work Environment:
This is a remote, full-time position designed for professionals who can collaborate effectively in a remote-first environment. Strong communication, independent problem-solving, ownership, and the ability to work across engineering and machine learning teams are important for success.
How to Apply for Senior Software Engineer Jobs in San Francisco 2026?
Interested candidates should review the current Senior Software Engineer opening through Mixedbread’s official recruitment channels.
When applying, prepare an updated resume highlighting your experience with software engineering, distributed systems, databases, AI infrastructure, search technology, or machine learning systems. Candidates should also demonstrate measurable examples of building, optimizing, or scaling production systems where possible.
Applicants should carefully review the current job description, location requirements, compensation information, eligibility for visa sponsorship, and other employment conditions before submitting an application.
Are senior software engineering positions available remotely today?
Yes, many senior software engineering positions offer remote work arrangements. Candidates should carefully review each employer’s location requirements, remote eligibility, working hours, and collaboration expectations before submitting an application.
What qualifications are needed for senior engineering roles?
Employers commonly seek production experience with Python, Go, Rust, distributed systems, databases, and scalable infrastructure. A computer science degree or equivalent practical experience may also be accepted for qualified candidates.
Can international engineers receive visa sponsorship for employment?
Some employers provide visa sponsorship and relocation assistance for eligible international candidates. Applicants should confirm sponsorship availability directly with the hiring organization because eligibility depends on the position, immigration requirements, qualifications, and company policies.
